How to Tell the Difference Between Sadness and Depression

Given how we use the words “sadness” and “depression” in everyday life and in pop culture, it can be hard to differentiate one from the other. Even though they might seem similar, they’re not. Experts say it’s like comparing a single star to a constellation. Understanding what separates sadness from depression is important, if it … Read more

Antidepressants Do Not Work by Numbing Emotions

Recent evidence from randomized, placebo controlled trials (1979 to 2016) has shown that, in about 15% of patients with depression, antidepressant treatment is robustly superior to placebo—contrary to the often-repeated claim that antidepressants are “not much better than a sugar pill.”1 It is not yet clear what clinical or biological features make this subgroup so … Read more

The Debate Over How Antidepressants Work Is Putting Millions of People in Danger

Nearly 10 percent of all Americans will experience symptoms of depression every year. One of the common forms of treatment includes a combination of therapy and antidepressants. According to the CDC, around 13 percent of Americans over the age of 18 were taking antidepressants between 2015 and 2018. The most commonly prescribed form of these … Read more

Why fatigue from long COVID goes beyond simply feeling tired

In a recent study posted to the medRxiv* preprint server, researchers in the Netherlands examined the role of inflammatory genes, cytotoxic T-lymphocytes (CD8+ T cells), and pro-inflammatory cytokines in long-lasting severe fatigue experienced by a large number of coronavirus disease 2019 (COVID-19) patients. Study: Severe fatigue as symptom of long COVID is characterized by increased … Read more

Even a Little Exercise Appears to Prevent Depression in New Study

photo† Ollie Millington †Getty Images† Research this month points to a mental health benefit from regularly exercising. The review found that people who reported being physically active were noticeably less likely to later be diagnosed with depression. This association was most apparent in people who appeared to meet the recommended amount of exercise a week, … Read more

All Kids Over 8 Should Get Routine Screening for Anxiety, Experts Recommend

Image† Getty †Getty Images† An influential panel of experts are recommending that children as young as 8 get routinely screened for anxiety. The recommendation adds to their previous guidance that children 12 or older should be screened for depression. However, they refrained from advising that children younger than 11 get depression screening or that children … Read more

Psilocybin Therapy Changes Brain Wiring in Depressed People, Study Finds

photo† Andrew Lichtenstein/Corbis †Getty Images† New research continues to find evidence that psilocybin—the active ingredient in psychedelic mushrooms—can uniquely help people with depression. The study found that people undergoing psilocybin-assisted therapy experienced noticeable changes in brain patterns associated with depression, including when compared to a control group. People also reported a reduction in their depression … Read more